Addictions
Head: Dr. Tony Toneatto
Cognitive Therapy for Problem
Gambling
Very little is known about treatments for problem gambling. This study
compares four cognitive-behavioural treatments commonly used to treat
substance addiction: cognitive therapy, behaviour therapy, motivational
therapy and minimal intervention. This randomized control trial will help
produce some clear answers on how to best help the gambling population.
Comorbidity of Pathological
Gambling, Psychiatric Disorders and Substance Use Disorders
Very little is known about the prevalence of pathological gambling among
clients seeking treatment for other addiction and/or mental health concerns.
This archival study will examine an existing large Ontario outpatient
clinical data set, in combination with chart reviews, to gain a better
understanding of how concurrent pathological gambling affects the clinical
course of treatment and treatment outcomes of addictive disorders.
Naltrexone Treatment
of Concurrent Alcohol Dependence and Pathological Gambling
There is growing interest in discovering effective medications for treating
problem gambling. Naltrexone has been found to be an effective medication
for treating alcohol addiction. Our belief that alcohol and gambling activate
similar rewarding-related brain sites gives us cause to believe that naltrexone
may also be helpful in treating gambling disorders. This study will compare
the effectiveness of naltrexone to a placebo in treating concurrent gambling
and alcohol addiction.
Concurrent Psychiatric
Disorders and Problem Gambling
This study will describe the history of other psychiatric disorders and
addiction problems in individuals who are gambling heavily, those who
have recovered from a gambling problem and non-problem or recreational
gamblers. Such information may help identify different sub-types of problem
gambling behaviour and influence treatment development.
Gambling Problems in
Males And Females in Ontario
The majority of our knowledge about problem gambling is based on the
study of men. To better understand this clinical condition, it is necessary
to learn more about women who have gambling problems. This study uses
a large number of gambling-related questionnaires to compare males and
females who have gambling problems. The questionnaires assess gambling
behaviour, gambling expectancies, gambling beliefs, self-esteem, stress,
social support, dissociation, problem-solving, psychiatric symptoms and
coping styles. Such information may help to develop more effective treatments
for gambling problems in both men and women.
Client-Centered Methadone
Treatment Program
The methadone program designed by one of CAMH's founding partners, the
Addiction Research Foundation, was redesigned to serve clients more efficiently
using a client-centred model and harm reduction principles. The new program
evaluates both clinical efficacy and cost-effectiveness using a newly
developed harm scale. This project has been fully integrated into the
clinical program and has been operating for four years.
Comparison of the Effects
of Heroin and Hydromorphone
This ongoing study will be the first to assess and compare the pharmacological
profiles of heroin and hydromorphone, to determine whether the acute subjective
and physiological effects of heroin and hydromorphone differ and to discover
whether the route of administration (intravenous versus subcutaneous)
alters the time course of their effects.
Smoking Cessation
This is a randomized double blind placebo-controlled 12-week smoking
cessation trial of Zyban (150 mg bid). It is a Phase IV multi-centre clinical
efficacy and safety trial of Zyban in adult smokers previously treated
with Zyban, who failed in treatment or relapsed after treatment.
CBT for Concurrent Panic
Disorder and Alcohol Problems
The goal of this study is to improve treatment for concurrent panic disorder
and alcohol problems. This will be done by comparing a treatment specifically
designed for this type of concurrent disorder to two other treatments
that target either the anxiety disorder alone or the alcohol problem alone.
The results will tell us whether it is necessary to specifically treat
both components of this concurrent disorder.
Prescription Opioid Dependence
Oral prescription opioid dependence, its causes, comorbidity and outcomes
are poorly understood. This study will help us understand the characteristics
of people dependent on oral prescription opioids and compare them to people
on other opioids (such as heroin). It may also help us to understand the
role of dysphoric mood and pain (and its neurobiological correlates) in
how problems develop and possibly find treatment alternatives for these
problems.
Adolescent Heroin Use
Available evidence suggests that heroin use by adolescents is on the
rise. There is a significant lack of appropriate treatment services for
these young people. The objectives of this study are to determine the
patterns of heroin use in a group of young people, identify the barriers
to accessing treatment, identify other relevant issues in their lives
that may affect the success
of a treatment program and allow participants to see their own contribution
to developing the treatment program.
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